Using Pittsburgh compound B based PET imaging, the following movie shows the accumulation of amyloid plaques in carriers of autosomal dominant AD mutations. The movie starts 25 years before, and ends 10 years after, the expected onset of clinical symptoms.
Pre and post therapy (2 mo.) MRI scan comparison of a 61 year old female with metastatic breast cancer at the level of the enhancing metastatic tumor. Prior to treatment (top row) there is elevation of the OEF at the site of the tumor. Following stereotactic radiosurgery (bottom row), the tumor is slightly smaller on post Gadolinium contrast T1 weighted images (left), but has markedly decreased OEF (right).