This project, funded by the NIH Eye Institute, aims to define the neural systems involved in attentional control of spatial behavior. We have identified a set of parietal and frontal areas that are active when attention and/or eye movements are directed toward relevant target locations (see Neuron 1998). These areas are also recruited during the selection of other visual attributes like direction of motion (fMRI of visual motion and attention) (see Neuroscience 1999). In particular, areas within the intraparietal sulcus are active when we voluntarily orient toward a location, whereas areas on the supramarginal and superior temporal gyrus (temporo-parietal junction) are active when we re-orient toward novel unattended stimuli (see Nature Neuroscience 2000). The activation of the temporo-parietal junction is strikingly lateralized to the right hemisphere, where lesions cause unilateral spatial neglect (neglect).